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Magnetic beads are used as materials for cell experiments, DNA purification and disease observation, and can also be used as materials for direct treatment. This AccuNanoBead™ have the advantages of high Binding Capacity due to their relatively large surface area because they are nano-sized.
BOINEER’s COOH Magnetic Beads for NGS are coated with high-density Carboxyl (COOH) groups on the surface of Silica Magnetic Beads. Depending on the size, COOH Magnetic Beads are available as irregular AccuNanoBead™. All magnetic beads developed by BIONEER have a pure magnetite (iron(Ⅱ, Ⅱ) oxide, Fe3O4) core. Compared to other beads that use polymer cores, BIONEER’s magnetic beads have higher magnetic saturation, allowing them to be collected more quickly by a magnet. This enables faster separation and purification of target biomolecules. Additionally, BIONEER’s technology allows for more functional groups to be attached to the surface, increasing the efficiency of experiments by capturing more target biomolecules with the same volume as magnetic beads. COOH functional groups form covalent bonds with biomolecules containing amine groups. This allows COOH Magnetic Beads to purify large proteins. Using the MagListo™ Magnetic Separation Rack (TM-1000, TM-1010, TM-1011, TM-1020, TM-1030) or other magnetic separation racks, biomolecules attached to the beads can be easily purified by magnetic force.
Features & Benefits
A high magnetic density of 80.8 emu/g derived from a pure magnetite(Fe3O4) core
Rapid magnetic capture within 5 seconds with a high magnetic density
(Black - BIONEER AccuNanoBead™, Brown - Competitor's polymer core product)
A high binding capacity of target molecules because of highly dense functional groups and smaller size
Microplastics-free as no plastic cores like polystyrene
Applications
Isolating and purifying amine-containing biomolecules from samples
Isolating and purifying DNA, RNA for NGS, proteins, antibodies, cells, small molecules, etc.
Figure 1. FE-SEM images of AccuNanobead™. Through them, it is possible to confirm that AccuNanobead™is close to a spherical shape.
▶ Size distribution
Figure 2. Size distribution of AccuNanoBead™. It can be seen that the average size of AccuNanoBead™ is about 400 nm.
▶ Comparison of magnetic beads shapes
Figure 3. Comparison of BIONEER's nano-sized magnetic beads(a) and competitors' magnetic beads(b~e) through electron microscopy images. It shows BIONEER's magnetic beads are rounder than those of its competitors. (a) BIONEER's magnetic beads (b) Company A's magnetic beads (c) Company B's magnetic beads (d) Company C's magnetic beads (e) Company D's magnetic beads