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Silica Coated Magnetic Beads(AccuNanoBead,200 nm,0.5 g,25 ml)
Silica Coated Magnetic Beads(AccuNanoBead,200 nm,0.5 g,25 ml)
Magnetic beads are used as materials for cell experiments, DNA purification and disease observation, and can also be used as materials for direct treatment. This AccuNanoBead™ have the advantages of high Binding Capacity due to their relatively large surface area because they are nano-sized.
BIONEER’s Silica-coated Magnetic Beads are products with high-density silica (SiO2) coating on the paramagnetic material, magnetite (iron(Ⅱ,Ⅲ) oxide, Fe3O4) surface. Depending on the size, Silica-coated Magnetic Beads are available as micrometer-sized AccuBead™ (1 - 5 μm) and nanometer-sized AccuNanoBead™ (200 nm/400 nm). All magnetic beads developed by BIONEER have pure magnetite as a core. Compared to other beads that use a polymer core, BIONEER’s magnetic beads have higher magnetic saturation, allowing for faster collection by a magnet. This enables more rapid separation and purification of target biomolecules. Additionally, BIONEER’s technology attaches more functional groups to the same surface area, allowing for capturing more target biomolecules with the same volume of magnetic beads, thus maximizing experimental efficiency. The hydroxyl groups of silica bind to sodium cations, which in turn bind to nucleic acids (DNA/RNA) in the presence of chaotropic salts (guanidine hydrochloride, guanidine thiocyanate, and sodium iodide). Utilizing this, Silica-coated Magnetic beads can isolate and purify nucleic acids from samples. This product magnetically isolates and purifies nucleic acids using the MagListo™ Magnetic Separation Rack (TM-1000, TM-1010, TM-1011, TM-1020, TM-1030) or other magnetic separation racks.
Features & Benefits
A high magnetic density of 80.8 emu/g derived from a pure magnetite(Fe3O4) core
Rapid magnetic capture within 5 seconds with a high magnetic density
(Black - BIONEER AccuNanoBead™, Brown - Competitor's polymer core product)
A high binding capacity of target molecules because of highly dense functional groups and smaller size
Microplastics-free as no plastic cores like polystyrene
Applications
Isolating and purifying Nucleic acids(DNA/RNA) from samples
Isolating and purifying Plasmid DNA, genomic DNA, RNA, PCR product, etc.
Figure 1. FE-SEM images of AccuNanobead™. Through them, it is possible to confirm that AccuNanobead™is close to a spherical shape.
▶ Size distribution
Figure 2. Size distribution of AccuNanoBead™. It can be seen that the average size of AccuNanoBead™ is about 400 nm.
▶ Comparison of magnetic beads shapes
Figure 3. Comparison of BIONEER's nano-sized magnetic beads(a) and competitors' magnetic beads(b~e) through electron microscopy images. It shows BIONEER's magnetic beads are rounder than those of its competitors. (a) BIONEER's magnetic beads (b) Company A's magnetic beads (c) Company B's magnetic beads (d) Company C's magnetic beads (e) Company D's magnetic beads