Silica Coated Magnetic Beads

BIONEER’s Silica-coated Magnetic Beads are products with high-density silica (SiO₂) coating on the paramagnetic material, magnetite (iron(Ⅱ,Ⅲ), Fe₃O₄) surface. The hydroxyl groups of silica bind to sodium cations, which in turn bind to nucleic acids (DNA/RNA) in the presence of chaotropic salts. Utilizing this, Silica-coated Magnetic beads can separate and purify nucleic acids from samples. This product can be used in isolating and purifying Nucleic acids sing the MagListo™ Magnetic Separation Rack (TM-1000, TM-1010, TM-1011, TM-1020, TM-1030) or other magnetic separation racks.

As low as $195.00

Cat. No.

Product Overview

Overview

BIONEER’s Silica-coated Magnetic Beads are products with high-density silica (SiO₂) coating on the paramagnetic material, magnetite (iron(Ⅱ,Ⅲ) oxide, Fe₃O₄) surface. Depending on the size, Silica-coated Magnetic Beads are available as micrometer-sized AccuBead™ (1 - 5 μm) and nanometer-sized AccuNanoBead™ (200 nm/400 nm). All magnetic beads developed by BIONEER have pure magnetite as a core. Compared to other beads that use a polymer core, BIONEER’s magnetic beads have higher magnetic saturation, allowing for faster collection by a magnet. This enables more rapid separation and purification of target biomolecules. Additionally, BIONEER’s technology attaches more functional groups to the same surface area, allowing for capturing more target biomolecules with the same volume of magnetic beads, thus maximizing experimental efficiency. The hydroxyl groups of silica bind to sodium cations, which in turn bind to nucleic acids (DNA/RNA) in the presence of chaotropic salts (guanidine hydrochloride, guanidine thiocyanate, and sodium iodide). Utilizing this, Silica-coated Magnetic beads can isolate and purify nucleic acids from samples. This product magnetically isolates and purifies nucleic acids using the MagListo™ Magnetic Separation Rack (TM-1000, TM-1010, TM-1011, TM-1020, TM-1030) or other magnetic separation racks.

Features & Benefits

A high magnetic density of 80.8 emu/g derived from a pure magnetite(Fe₃O₄) core

Rapid magnetic capture within 5 seconds with a high magnetic density

(Black - BIONEER AccuNanoBead™, Brown - Competitor's polymer core product)

A high binding capacity of target molecules because of highly dense functional groups and smaller size

Microplastics-free as no plastic cores like polystyrene

Applications

Isolating and purifying Nucleic acids(DNA/RNA) from samples

Isolating and purifying Plasmid DNA, genomic DNA, RNA, PCR product, etc.

Technical/Specs

▶ Specifications

Product	AccuNanoBead™
Average Size	400 nm	200 nm
Density	5.08 g/mL	4.84 g/mL
Surface Area	6.5 m²/g	59.1 m²/g
Maximum Binding Capacity (per 1mg-beads)	10 μg of Nucleic Acids	18 μmol of Nucleic Acids
Magnetic Saturation	80.8 emu/g	80.2 emu/g
Number of Beads (per gram)	6.143 × 10¹²	4.602 × 10¹³
Solvent	D.W.
Recommended Concentration	20 mg/mL
Experimental Temperature	Room Temperature
pH	pH 7
Storage Temperature	Room Temperature
Dangerous Goods	None

▶ Electron microscopy image (FE-SEM and TEM)

Figure 1. FE-SEM images of AccuNanobead™. Through them, it is possible to confirm that AccuNanobead™ is close to a spherical shape.

▶ Size distribution

Figure 2. Size distribution of AccuNanoBead™. It can be seen that the average size of AccuNanoBead™ is about 400 nm.

▶ Comparison of magnetic beads shapes

Figure 3. Comparison of BIONEER's nano-sized magnetic beads(a) and competitors' magnetic beads(b~e) through electron microscopy images. It shows BIONEER's magnetic beads are rounder than those of its competitors.
(a) BIONEER's magnetic beads
(b) Company A's magnetic beads
(c) Company B's magnetic beads
(d) Company C's magnetic beads
(e) Company D's magnetic beads

Literature/Support

◈ Quality Assurance

Bioneer is the holder of Quality Management System Certificates for the following standards.

• ISO 9001 – certificate

• EN ISO 13485 - certificate

Ordering Info

▶ Ordering Information

Magnetic Nanobeads are coated for various functions and sold for research and separation.

Cat. No.	Product Description	Option	Price
TA-1010-1	AccuNanoBead ™ Silica Magnetic Nanobeads, size 400nm	0.5 g/25 ml	$250.00
TA-1010-2		1.0 g/50 ml	$450.00
TA-1010-3		10 g/500 ml	$2,550.00
TB-1010-1	AccuNanoBead ™ Silica Magnetic Nanobeads, size 200nm	0.5g/25ml/EA	$375.00
TB-1012-1	AccuNanoBead ™ COOH Magnetic Nanobeads, size 400 nm	0.5 g	$435.00
TA-1011-1	AccuNanoBead ™ NH2 Magnetic Nanobeads, size 400 nm	0.5 g	$280.00
TA-1012-1	AccuNanoBead ™ COOH Magnetic Nanobeads, size 400 nm	0.5 g	$290.00
TA-1013-1*	AccuNanoBead ™ Epoxy Magnetic Nanobeads, size 400 nm	0.5 g	$310.00
TA-1014-1	AccuNanoBead ™ C18 Magnetic Nanobeads, size 400 nm	0.5 g	$310.00
TA-1015-1*	AccuNanoBead ™ Streptavidin Magnetic Nanobeads, size 400 nm	50 mg/5 ml	$420.00
TB-1015-1*	AccuNanoBead ™ Streptavidin Magnetic Nanobeads, size 200 nm	50 mg/5 ml	$1,050.00
TA-1016-1*	AccuNanoBead ™ Biotin Magnetic Nanobeads, size 400 nm	0.5 g/25 ml	$310.00
TA-1017-1	AccuNanoBead ™ Ni-NTA Magnetic Nanobeads, size 400 nm	0.5 g/25 ml	$510.00
TA-1019-1	AccuNanoBead ™ Thiol Magnetic Nanobeads, size 400 nm	0.5 g	$380.00
TA-1021-1	AccuNanoBead ™ Protein G Magnetic Nanobeads, size 400nm	40 ml/ 1 ml, 1 ea	$152.00
TA-1021-5		40 ml/ 1 ml, 5 ea	$522.00
TA-1021-10		40 ml/ 1 ml, 10 ea	$800.00
TA-1022-1	AccuNanoBead ™ Protein A Magnetic NanoBeads, size 400 nm	40 ml/ 1 ml, 1 ea	$152.00
TA-1022-5		40 ml/ 1 ml, 5 ea	$522.00
TA-1022-10		40 ml/ 1 ml, 10 ea	$800.00
TF-1012-1	COOH Magnetic Beads for NGS	500 mg	$590.00
TF-1012-2		1 g	$990.00
TF-1012-3		4 g	$2,800.00
TS-1000-1	Magnet Φ15x1.5 and Screw Tube 1.5 ml	1 set	$5.00

* It is shipped in ice packing.

** Please inquiry for bulk orders.

▶ Related Products

Cat. No.	Product Description	Option
K-7250	AccuRapid ™ Cell-Free Protein Expression Kit	45 ul x 24 reactions
K-7300	ExiProgen™ EC Protein Synthesis Kit	16 reactions
K-7301		32 reactions
K-7302		96 reactions
D-2010	AccuLadder™ Protein Size Marker (Broad)	500 ul
D-2020	AccuLadder™ Protein Size Marker (Low)	500 ul
K-7220	ExiProgen™ His-tagged Protein Purification Kit	16 reactions
K-7200	ExiProgen™ His-tagged Protein Purification Kit	5 reactions

▶ Technical Support and Ordering

For more information on our products, please contact us by email.
nano-support@bioneer.com