Gene Synthesis Custom Order

1. Open Bioneer homepage(www.bioneer.co.kr) and click on Gene Synthesis Service Page.

2. Log in.

3. Enter the necessary information and confirm the quotation.

4. Click Add to Cart button; then place your final order.
Synthesis will start on the same day if the orders are placed before 16:00. Otherwise, it will start on the next day.
This service is unavaliable during the holiday period. 

There is no limit in length. However, genes that go over 3Kb will take a long time.

Those orders will be require consultation. 

Not that as gene synthesis of vector construction is done differently from the normal synthesis, its price and the duration time will also not be same.

Ordered genes are provided in the form of 2 to 5 ug dried plasmid DNA cloned in the basic vector.

Please refer to the table below to see the price of gene synthesis having simple sequences.

The cost and delivery time will be extended for genes with structures complicated for synthesis such as having a high GC content ratio, or tandem repeat, inverted repeat, or homo-polymeric sequence.

Furthermore, synthesis of genes inhibiting growth or having toxicity to E. coli will increase the service price (by 20%) and time. The extended period is unable to be estimated.

For the No guarantee gene, the synthesis period is not guaranteed, and the synthesis period shown in the quotation is the average synthesis period.

This service synthesizes oligonucleotides and utilizes staggered hybridization, ligation, and PCR reactions for gene synthesis. Having repetitive sequences makes the hybridization processes difficult, increasing the difficulty ot the synthesis. 

In this case, additional oligonucleotide designs are required with further synthesis and tests. Thus, additonal fees will cost, greatly varying on the length and type of the repeat sequence.

Yes, it can be done through a seperate cloning service. While ordering this service, select "Gene synthesis & Cloning" and specify the what you need (such as providing vector samples to us, enzyme sites, etc.). After checking the price, you can finalize your orders.

Furthermore, we offer 50% discount if the cloning service is ordered with the gene synthesis service.

Normally, the plasmids should last a year at -20℃.

This service is only capable of synthesizing linear double-stranded DNA with a length of 1 kb or less without high GC conents or any tandem repeats, inverted repeats, or homo-polymeric sequences.

If your genes have features that inhibit the synthesis such as high & low GC, repeats, or inverted sequences, please use Gene Synthesis service.

Please use the gene synthesis service instead if you cannot please the order because of the above reason.

If you can not place your order for the above reason, please use Gene synthesis service instead of AccuGeneBlock service.

Yes, you can use the codon optimization site on the homepage to not only check the best codons, but also modify your codons directly.

We use a codon optimization program developed together with Bioneer and KAIST.

We categorize those containing Select Agents and Toxin sequences described in the Harmonized screening protocol of the International Gene synthesis Consortium (IGSC) as "Risk sequences."

Yes you may. However, we only provide risk sequences to bona fide research agents with meticulous screening. Buyers must sign a written consent form to indicate that they agree to use our Risk sequences only for research purposes.

All services are available online on our website.

After selecting the desired services and writing the required information, you may check the quotation to finalize your orders. Order will be confirmed once your payment is complete.

We do have a policy for a mass synthesis order. Please contact us separately.

If you want to change the sequence:

Yes, both are possible. However, while we offer directional cloning service for free, a fee of $100 will be charged per additional 100 µg of vector, requiring five more days for completion.

Add 20ul (Final 250ng / ul) of DW or TE buffer to the delivered DNA. (It is recommended to add DW or TE buffer to tubes and store at 4℃ for 10 minutes.)

For the long-term storage, refrigerate it at -20°C. However, you can store at the room temperature if the DNA is in dried state.

We safely store your ordered genetic information along with the finished products for six months. Contact us to immediately discard them after the synthesis.