Oligo Synthesis

Oligo synthesis

DNA

All oligos provided by Bioneer are applied to the AccuOligo® system, and all oligos are produced in a clean room and supplied to customers in a DNase, RNase, and DNA free state. Generally, supplied oligos go through synthesis, purification, QC, and dispensing processes, are dried, and are then delivered to customers. In the case of conventional synthesis services, there is a chance that dried oligos may fall during their delivery from shaking and impacts.

If the containers are opened during the delivery, parts of oligos may fall out, leading to yield loss. This may be much more severe when ordered in plates as cross-contaminations may occur. AccuOligo® technology allows the synthesized oligonucleotides to stick at the bottom of the tube even under intense vibrations. (Dried oligonucleotide composition of the new patent application’ Patent 2006 Registration Number 10-0777249)

Order

Preventing dislodging and loss of oligos during production, packaging, and shipping

Containing “Leak Inhibitors” not affecting protocols such as PCR, Sequencing, Enzyme cutting, etc.

Overcomes the phenomenon of small amounts of Oligo adhering to the lid

Prevent contamination between each well in the plate

Order

Thorough quality control

A total of 7 MALDI-TOF spectrometers are used to conduct QC inspection.
High-quality oligo

Supply of nuclease-free, DNA-free oligo by synthesizing in a clean room and eliminating truncated failures including n-1 mer with our proprietary Bio-RP high-purity purification system.
Exact concentration

To deliver with exact concentration, Bioneer use automatic dosing dispenser and Accuoligo® technology, to prevent the loss of oligo during transportation and opening.
Automated production

By establishing the world's first automated production line process, the entire process from ordering to synthesis, QC, and packaging is automated and produced using the ‘Computer Aided Manufacturing (CAM) system.’
Mass production capacity

Able to produce maximum of 30,500 synthetic genes per day, and large-scale synthesis in mg to kg units is possible.

Oligo Synthesis

Oligo synthesis

DNA

RNA