AccuPower® EAE PCR Kit is a ready-to-use premix for PCR that can be used to detect E. coli in livestock by specifically amplifying the E. coli attachment effacement (EAE) gene.
※ This kit is for research use only and must not be used for diagnostic purposes.
E. coli enters the organs of animals and causes lesions. It is also a source of many infections such as acute urinary tract infections, peritonitis, hepatitis, sepsis, and meningitis. E. coli can be classified into various categories: enteropathogenic E. coli (EPEC), enterotoxigenic E. coli (ETEC), enteroinvasive E. coli (EIEC), enterohemorrhagic E. coli (EHEC), etc. Among those, intimin, the product of EAE gene, causes EPEC adhesion to intestinal epithelial cells, which may develop into microvilli atrophy, polar actin, etc. Furthermore, intimin protein can also induce pathogenic characteristics to EHEC and EPEC by inducing bacterial adhesion, which develops into A/E lesions.