AccuPower® Warfarin genotyping Kit

AccuPower® Warfarin genotyping Kit is an in vitro diagnostic kit designed to determine the genotype of VKORC1 and CYP2C9 gene SNPs related to warfarin dosing through real-time PCR.

Product Description

Warfarin as a coumarin derivative is an anticoagulant that inhibits the biosynthesis of coagulant factor. Determining an optimal warfarin dose is essential to reduce side effect like hemorrhage. With this, analysis of SNPs in the genes, VKORC1 and CYP2C9, is shown to be closely related to the metabolism of anticoagulation drugs such as warfarin in individuals. This is why a fast and reliable test method is essential for prompt dose adjustment to prevent serious over- or under-dosing effects.

Features and Benefits

Signature Convenience: Distinct and direct detection of warfarin SNP genotype through allele-specific PCR method.
Enhanced Sensitivity & Specificity: Bioneer’s proprietary HotStart technology accomplishes high sensitivity and specificity.
Remarkable Stability: Vacuum-dried premix allows stable and reproducible results.
High Quality: All diagnostic kits manufactured by Bioneer are under strict quality control guidelines.

Specifications

Specimen Type	Human whole blood, buccal swab
Detectable Range	10 ng/test ~ 200 ng/test
Kit Contents	PCR Premix, PCs (W1/W2/W3/W4/W5/W6/W7/W8), DEPC D.W
Instrumentation	Exicycler™ 96 with ExiGenotyper™ software
Tests	12

Performances

AccuPower® Warfarin genotyping Kit includes Positive Control (PC) and Internal Positive Control (IPC) for accurate and reliable genotyping of VKORC1 and CYP2C9 gene SNP. If the assay is valid, the genotype of each SNP is heterotype.

User centric ExiGenotyper software automatically analyzes the test results. The genotype of each SNP is determined by delta Ct (thermal cycle) value between the mutant type amplification and the wild type amplification.

Ordering Information

Cat. No.	Product Description
WAF-1111	AccuPower® Warfarin genotyping Kit

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Quality Assurance

Bioneer is the holder of Quality Management System Certificates for the following standards.

ISO 13485 - certificate

Contact Us

E-mail : sales@bioneer.com