AccuPower® ApoE Real-Time PCR Kit

AccuPower® ApoE Real-Time PCR Kit is an in vitro diagnostic kit designed to determine the genotype of human apolipoprotein E (ApoE) SNP related to Alzheimer's disease through real-time PCR.

Product Description

Human apolipoprotein E (ApoE) is a major component of lipoproteins and has an important role in lipoprotein metabolism. ApoE has 3 common alleles (ε2, ε3, ε4) which encode three isoforms of ApoE protein E2, E3, and E4. Apo E was first noticed for its importance related to lipoprotein metabolism and cardiovascular diseases, but recently, ApoE gene research uncovered links to Alzheimer’s disease, immune system control and intelligence. There is a reported 60% concordance between Alzheimer patients and the ApoE gene.

Features and Benefits

Signature Convenience: Distinct and direct analysis of ApoE 6 genotype (E3/E3, E2/E3, E2/E2, E3/E4, E2/E4, E4/E4) through allele-specific PCR method.
Enhanced Sensitivity & Specificity: Bioneer’s proprietary HotStart technology accomplishes high sensitivity and specificity.
Remarkable Stability: Vacuum-dried premix allows stable and reproducible results.
High Quality: All diagnostic kits manufactured by Bioneer are under strict quality control guidelines.

Specifications

Specimen Type	Human whole blood, buccal swab
Detectable Range	10 ng/test ~ 200 ng/test
Kit Contents	PCR Premix, PCs (E1/E3), DEPC D.W
Instrumentation	Exicycler™ 96 with ExiGenotyper™ software
Tests	24

Performances

AccuPower® ApoE Real-Time PCR Kit includes Positive Control (PC) and Internal Positive Control (IPC) for accurate and reliable genotyping of ApoE. If the assay is valid, the genotype of PC is heterotype for both SNP 112 and 158, and the final result is E2/E4.

AccuPower® ApoE Real-Time PCR Kit test results using clinical samples. The kit employs IPC in all wells to confirm correct PCR amplification.

User centric ExiGenotyper software automatically analyzes the test results. ApoE final results are determined by 2 SNP (112, 158) genotypes. The genotype of each SNP is determined by delta Ct (thermal cycle) value between the mutant type amplification and the wild type amplification.

Ordering Information

Cat. No.	Product Description
APE-1111	AccuPower® ApoE Real-Time PCR Kit

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Quality Assurance

Bioneer is the holder of Quality Management System Certificates for the following standards.

ISO 13485 - certificate

Contact Us

E-mail : sales@bioneer.com